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Urinary Tract Infection Vaccines
Studies from University of Michigan update current data on urinary tract infection vaccines
February 25th, 2009
Researchers detail in 'Vaccination with proteus toxic agglutinin, a hemolysin-independent cytotoxin in vivo, protects against Proteus mirabilis urinary tract infection,' new data in urinary tract infection. "Complicated urinary tract infections (UTI) caused by Proteus mirabilis are associated with severe pathology in the bladder and kidney. To investigate the roles of two established cytotoxins, the HpmA hemolysin, a secreted cytotoxin, and proteus toxic agglutinin (Pta), a surface-associated cytotoxin, mutant analysis was used in conjunction with a mouse model of ascending UTI," investigators in the United States report. "Inactivation of pta, but not inactivation of...
Source: Vaccine Weekly (2009-02-25)
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