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HIV/AIDS
New findings from MS Center describe advances in HIV/AIDS
February 25th, 2009
According to a study from Manguinhos, Brazil, "Rhesus monkeys are relevant models for human diseases. The simian immunodeficiency virus (SIV) infection is an useful macaque model for assessing human immunodeficiency virus (HIV) vaccine strategies." "Susceptibility and resistance to viruses have been associated with particular major histocompatibility complex (MHC) molecules. Several epitopes in the HIV structural and non-structural protein restricted by distinct MHC class I haplotypes are important targets for human cytotoxic T lymphocytes, which mediate protection against SIVmac infection. Mamu-A*01, for example, is a MHC class I molecule of rhesus monkeys that...
Source: Vaccine Weekly (2009-02-25)
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