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Vaccine Weekly

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Adenovirus



Study findings on adenovirus are outlined in reports from Yokohama City University, Department of Molecular



February 25th, 2009

New investigation results, 'Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV infection of rhesus monkeys undergoing antiretroviral therapy,' are detailed in a study published in Gene Therapy. According to a study from Yokohama, Japan, "Antiretroviral therapy (ART) effectively slows the progression of AIDS. However, drug resistance and/or toxicity can limit the utility of ART in many patients."

"In this study, we assessed whether a viral vector-based vaccine can be used as a therapeutic vaccine in simian immunodeficiency virus (SIV)-infected monkeys. The effect of vaccinating SIVmac239-infected rhesus monkeys with an SIV gag and...


Source: Vaccine Weekly (2009-02-25)

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