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Vaccine Weekly

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Immunotherapy



Research data from University of Melbourne update understanding of immunotherapy



February 25th, 2009

Researchers detail in 'Safety, immunogenicity and efficacy of peptide-pulsed cellular immunotherapy in macaques,' new data in immunotherapy. According to recent research from Australia, "Simple and effective delivery methods for cellular immunotherapies are needed. We recently published on the effectiveness of using ex vivo pulsing of overlapping SIV Gag 15mer peptides onto fresh peripheral blood cells in 32 SIV(mac251)-infected pigtail macaques."

"We now report on the safety of this approach, analysis of a novel assay for immunogenicity, the effect of an MHC allele, Mane-A*10, on CD8 T cell escape occurring and disease outcome. The vaccine strategy was safe, with no...


Source: Vaccine Weekly (2009-02-25)

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