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Immunization
Findings from Technical University of Denmark provide new insights into immunization
February 25th, 2009
According to recent research from Lyngby, Denmark, "MHC: peptide binding plays a central role in activating the immune surveillance. Computational approaches to determine T-cell epitopes restricted to any given major histocompatibility complex ( MHC) molecule are of special practical value in the development of for instance vaccines with broad population coverage against emerging pathogens." "Methods have recently been published that are able to predict peptide binding to any human MHC class I molecule. In contrast to conventional allele-specific methods, these methods do allow for extrapolation to uncharacterized MHC molecules. These pan-specific human lymphocyte...
Source: Vaccine Weekly (2009-02-25)
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