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Hepatitis C Virus
Scientists at Wuhan University describe research in hepatitis C virus
March 4th, 2009
According to recent research from Wuhan, People's Republic of China, "The hepatitis C virus is a major cause of chronic liver disease worldwide. Lack of culture system supporting virus production has been one of the major impediments in HCV research and vaccine development." "Here, we use a HCV (1b) full-length cDNA clone that replicates and produces integrated and infectious virus particles in cultured Vero cells. Evidence shows that the replication of virus particles is robust, producing over 10 8 copies of positive RNA per milliliter of the culture cells within 48 h. Sucrose density gradient centrifugation of the cell lysate reveals that the HCV virions have a...
Source: Vaccine Weekly (2009-03-04)
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