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Vaccine Weekly

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Immunization



New immunization research from Kyoto Prefectural University outlined



March 4th, 2009

According to a study from Kyoto, Japan, "In melanoma patients vaccinated with monocyte-derived melanoma peptide-pulsed dendritic cells (DC), the delayed-type hypersensitivity (DTH) reactions have been examined as a surrogate marker to determine if acquired immunity is induced by DC vaccination. To date, however, only limited information has been reported as for histopathological analyses of DTH."

"To evaluate tumor-specific immunomonitoring histopathologically after DC vaccination in melanoma patients. Seven patients previously vaccinated with monocyte-derived melanoma peptide-pulsed DCs were challenged with recall antigenic peptide injection in the skin of the forearm....


Source: Vaccine Weekly (2009-03-04)

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