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Vaccine Weekly

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Immunization



New immunization study findings have been reported from D. Campbell et al



March 4th, 2009

According to a study from Fitzroy, Australia, "Over many decades, several attempts have been made to treat hypertension using a vaccination strategy to inhibit the renin-angiotensin system. Renin vaccination successfully inhibited renin activity and reduced blood pressure in animal models, but caused autoimmune disease of the kidney."

"By contrast, most previous studies of angiotensin vaccination failed to reduce blood pressure in animal models, despite producing high titers of antibodies that prevented the pressor response to exogenous angiotensins. Angiotensin vaccination is being revisited as a strategy for treating hypertension, in the hope that new conjugates of...


Source: Vaccine Weekly (2009-03-04)

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