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Immunization
Study findings from C.S. Andersen et al broaden understanding of immunization
March 4th, 2009
According to a study from Copenhagen, Denmark, "It is a long held belief that the strong immunostimulatory activity of the Mycobacterium bovis bacillus Calmette-Guerin vaccine and Freund's complete adjuvant is due to specific mycobacterial cell envelope components, such as lipids and polysaccharides. Implicated mycobacterial lipids include, among others, the so-called cord factor or trehalose dimycolate, but limited information is available regarding the precise molecular nature of the stimulatory components responsible for the interaction with human APCs." "In this regard, the majority of research aimed at identifying and characterizing individual immunostimulatory...
Source: Vaccine Weekly (2009-03-04)
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