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Vaccine Weekly

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Immunotherapy



Recent studies from St. James University add new data to immunotherapy



March 4th, 2009

According to recent research from Leeds, the United Kingdom, "Dendritic cells (DC) are under intense preclinical and early clinical evaluation for the immunotherapy of cancer. However, the optimal culture conditions and route of delivery for DC vaccination have not been established."

"Here we describe the first human application of DC matured with the bacterial agent OK432 (OK-DC), using a short-term serum-free culture protocol, which generates Mature DC from CD14(+) precursors after 5 days. These cells were prepared within the framework of a National Blood Service facility, demonstrating that DC represent a product which is potentially deliverable alongside current...


Source: Vaccine Weekly (2009-03-04)

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