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Vaccinia Virus Immunology
Studies from University of Copenhagen in the area of vaccinia virus immunology published
March 4th, 2009
Current study results from the report, 'High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4+ T cell responses more than 30 years post-vaccinia virus vaccination,' have been published. "Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K(D) <or=5 nM)," investigators in Netherlands report. "However, five of the individuals tested did not show typical...
Source: Vaccine Weekly (2009-03-04)
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