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Vaccine Weekly

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Cancer Vaccines



New cancer vaccines study findings have been published by scientists at University of North Carolina



March 4th, 2009

According to recent research published in the Journal of Immunology, "With a 5-year survival rate of < 5%, pancreatic cancer is one of the most rapidly fatal malignancies. Current protocols for the treatment of pancreas cancer are not as effective as we desire."

"In this study, we show that a novel Mucin-1 (MUC1)-based vaccine in combination with a cyclooxygenase-2 inhibitor (celecoxib), and low-dose chemotherapy (gemcitabine) was effective in preventing the progression of preneoplastic intraepithelial lesions to invasive pancreatic ductal adenocarcinomas. The study was conducted in an appropriate triple transgenic model of spontaneous pancreatic cancer...


Source: Vaccine Weekly (2009-03-04)

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