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HIV/AIDS
Study data from E. Carnero and co-authors update knowledge of HIV/AIDS
March 4th, 2009
"One attractive strategy for the development of a human immunodeficiency virus (HIV) vaccine is the use of viral vectors with a proven safety profile and an absence of preexisting immunity in humans, such as Newcastle disease virus (NDV). Several NDV vaccine vectors have been generated, and their immunogenicities have been investigated with different animal models," scientists in the United States report. "However, a systematic study to evaluate the optimal insertion site of the foreign antigens into NDV that results in enhanced immune responses specific to the antigen has not yet been conducted. In this article, we describe the ability of NDV expressing HIV Gag to...
Source: Vaccine Weekly (2009-03-04)
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