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Vaccine Weekly

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HIV/AIDS



Study findings from D.N. Sather et al provide new insights into HIV/AIDS



March 4th, 2009

According to a study from the United States, "The characterization of the cross-reactive, or heterologous, neutralizing antibody responses developed during human immunodeficiency virus type 1 (HIV-1) infection and the identification of factors associated with their generation are relevant to the development of an HIV vaccine. We report that in healthy HIV-positive, antiretroviral-naive subjects, the breadth of plasma heterologous neutralizing antibody responses correlates with the time since infection, plasma viremia levels, and the binding avidity of anti-Env antibodies."

"Anti-CD4-binding site antibodies are responsible for the exceptionally broad cross-neutralizing...


Source: Vaccine Weekly (2009-03-04)

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