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Immunology
Findings from University of Minnesota advance knowledge in immunology
March 11th, 2009
According to a study from the United States, "The T(H)1-T(H)2 paradigm provides an elegant model of directed response to infectious pathogens. Developed in the mouse, the model has provided a framework for systematic and mechanistic studies of immune regulation, protective immunity, and vaccine development in swine." "Interleukin-4 (IL-4) plays a central role in the paradigm as a regulatory molecule directing development of the T(H)2 phenotype, as a developmental cytokine essential for antibody production, and as a soluble diagnostic marker of the T(H)2 cell type. In contrast, while characterizing the biological properties of porcine IL-4, we discovered that it was not...
Source: Vaccine Weekly (2009-03-11)
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