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Vaccine Weekly

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Life Sciences



Researchers from University of Lubeck detail new studies and findings in the area of life sciences



March 11th, 2009

According to recent research from Lubeck, Germany, "A number of immunological functions are dependent on circadian rhythms and regular sleep. This has impact on the type and magnitude of immune responses following antigenic challenge, for example in vaccination."

"Little is known about the underlying mechanisms. One possibility may be the circadian and sleep-dependent modulation of CD4(+)CD25(-) T cell responses by CD4(+)CD25(+) natural regulatory T cells (nT(reg)). In a variety of studies, nT(reg) have been shown to regulate T cell responses negatively. Thus, we investigated the influence of sleep and circadian rhythm on the number and function of nT(reg) as well as on...


Source: Vaccine Weekly (2009-03-11)

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