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Salmonellosis
Research reports on salmonellosis from M. Malcova and colleagues provide new insights
March 11th, 2009
According to a study from Brno, Czech Republic, "aro mutants of Salmonella enterica are frequently used as live vaccines for the oral vaccination of domestic animals. Interestingly, besides their auxotrophy, they appear to be of reduced resistance to the components of innate immune response due to a defect in outer membrane and/or cell wall integrity." "Because different extracellular structures associated with the cell wall or outer membrane are involved in biofilm formation, we were interested in the ability of aroA and aroD mutants of S. Enteritidis to adhere to solid surfaces. We found that aroA and aroD mutants did not adhere to solid surfaces although they bind...
Source: Vaccine Weekly (2009-03-11)
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