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Vaccine Weekly

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Salmonellosis



Studies from University of Ghent in the area of salmonellosis published



March 11th, 2009

According to a study from Merelbeke, Belgium, "Salmonella Typhimurium infections in pigs pose an important human health hazard. One promising control measure is the development of live attenuated vaccine strains using defined knockout mutants."

"Preferably, screening of candidate knockout vaccine strains for attenuation should first be done in models allowing testing of a large number of strains. Thereafter, a limited number of selected strains should be further characterized in an experimental infection model in pigs. The aim of the present study was to develop such models. The invasive and proliferative characteristics of S. Typhimurium were assessed in both a...


Source: Vaccine Weekly (2009-03-11)

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