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DNA Vaccines
Researchers at Technical University, University Health Science Center target DNA vaccines
March 11th, 2009
Current study results from the report, 'Sm-p80-based DNA vaccine formulation induces potent protective immunity against Schistosoma mansoni,' have been published. According to a study from the United States, "No effective vaccine exists for the human parasitic disease, schistosomiasis. We have targeted a functionally important antigen, Sm-p80 as a vaccine candidate because of its consistent immunogenicity, protective potential and important role in the immune evasion process." "In this study we report that a Sm-p80-based DNA vaccine formulation confers 59% reduction in worm burden in mice. Animals immunized with Sm-p80-pcDNA3 exhibited a decrease in egg production by...
Source: Vaccine Weekly (2009-03-11)
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