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HIV/AIDS
New findings from A. Duda and co-researchers in the area of HIV/AIDS described
March 11th, 2009
According to recent research published in the Journal of Virology, "Human immunodeficiency virus type 1 (HIV-1) can evade immunity shortly after transmission to a new host but the clinical significance of this early viral adaptation in HIV infection is not clear. We present an analysis of sequence variation from a longitudinal cohort study of HIV adaptation in 189 acute seroconverters followed for up to 3 years." "We measured the rates of variation within well-defined epitopes to determine associations with the HLA-linked hazard of disease progression. We found early reversion across both the gag and pol genes, with a 10-fold faster rate of escape in gag (2.2...
Source: Vaccine Weekly (2009-03-11)
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