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Influenza
Research from Y.F. Yang and co-researchers in the area of influenza described
March 11th, 2009
According to a study from the United States, "Cytokines have been used extensively as adjuvants in vaccines. However, practical considerations limit their use; diffusion from antigen, short half-lives and additional production costs." "To address these problems we have developed a technology that efficiently produces inactivated, whole-virus influenza vaccine bearing membrane-bound cytokines. To provide ''proof of principle,'' we chose chicken interleukin-2 (IL-2) and chicken granulocyte -macrophage colony-stimulating factor. Fusion constructs were generated in which their coding regions were linked to the influenza virus transmembrane encoding domains of the...
Source: Vaccine Weekly (2009-03-11)
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