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Porcine Reproductive And Respiratory Syndrome
Data on porcine reproductive and respiratory syndrome discussed by researchers at University of Texas
March 11th, 2009
According to recent research published in the journal Virus Genes, "Developing a vaccine that can differentiate infected and vaccinated animals (DIVA) is a new challenge in the design of a vaccine for porcine reproductive and respiratory syndrome virus (PRRSV). Nonstructural protein 2 (nsp2) is the single largest viral product, and it has multiple roles in polypeptide processing and replication complex formation." "Using reverse genetics and an infectious PRRSV cDNA clone, we constructed several deletion mutants in the non-essential region of nsp2. One mutant, which has a 131 amino acid deletion within a relatively conserved region of nsp2, was recovered and...
Source: Vaccine Weekly (2009-03-11)
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