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Vaccine Weekly

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Human Papillomavirus



Reports from College of Medicine highlight recent research in human papillomavirus



March 11th, 2009

According to a study from the United States, "Human papillomavirus type 18 (HPV18) and HPV45 account for approximately 20% of all cervix cancers. We show that HPV18, HPV45, and the recently discovered HPV97 comprise a clade sharing a most recent common ancestor within HPV alpha 7 species."

"Variant lineages of these HPV types were classified by sequence analysis of the upstream regulatory region/E6 region among cervical samples from a population-based study in Costa Rica, and 27 representative genomes from each major variant lineage were sequenced. Nucleotide variation within HPV18 and HPV45 was 3.82% and 2.39%, respectively, and amino acid variation was 4.73% and...


Source: Vaccine Weekly (2009-03-11)

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