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Cholera Vaccines



Investigators at Chonbuk National University, Research Center target cholera vaccines



March 18th, 2009

A new study, 'Immunogenicity of a cholera toxin B subunit Porphyromonas gingivalis fimbrial antigen fusion protein expressed in E. coli,' is now available. "The gram-negative anaerobic oral bacterium Porphyromonas gingivalis initiates periodontal disease through fimbrial attachment to saliva-coated oral surfaces. To study the effects of immunomodulation on enhancement of subunit vaccination, the expression in E. coli and immunogenicity of P. gingivalis fimbrial protein (FimA) linked to the C-terminus of the cholera toxin B subunit (CTB) were investigated," scientists in Korea report.

"Complementary DNAs encoding the P. gingivalis 381...


Source: Vaccine Weekly (2009-03-18)

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