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Life Sciences
Researchers from University of Maryland, Center for Vaccine Development report on findings in life sciences
March 18th, 2009
New investigation results, 'Post-transcriptional processing of the LEE4 operon in enterohaemorrhagic Escherichia coli,' are detailed in a study published in Molecular Microbiology. "Enterohaemorrhagic Escherichia coli (EHEC) employs a type III secretion system (T3SS) to export translocator and effector proteins required for mucosal colonization. The T3SS is encoded in a pathogenicity island called the locus of enterocyte effacement (LEE) that is organized in five major operons, LEE1 to LEE5," researchers in the United States report. "LEE4 encodes a regulator of secretion (SepL), translocators (EspA, D and B), two chaperones (CesD2 and L0017), a T3SS...
Source: Vaccine Weekly (2009-03-18)
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