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Vaccine Weekly

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Pertussis Vaccines



Studies from M. Riffelmann and colleagues provide new data on pertussis vaccines



March 18th, 2009

Fresh data on pertussis are presented in the report 'Antibody decay after immunisation of health-care workers with an acellular pertussis vaccine.' "Antibody decay after a single dose of acellular pertussis vaccine containing 25 microg of pertussis toxin (PT), 25 microg of filamentous hemagglutin (FHA), and traces of pertactin (PRN) was monitored in health-care workers. Blood was sampled 4 weeks (n=246), 1 year (n=187), 2 years (n=53), 3 years (n=134), and 4 years (n=37) after vaccination," scientists in Krefeld, Germany report.

"IgG anti-PT, IgG anti-FHA and IgG anti-PRN were measured by ELISA. Peak median antibodies to PT, FHA, and PRN were 314, 785, and 84 EU/ml...


Source: Vaccine Weekly (2009-03-18)

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