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Vaccine Weekly

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Allergies



New allergies study findings reported from J. Carnes and co-authors



March 18th, 2009

"Chemical modification of allergen vaccines to reduce IgE binding improves safety while maintaining clinical efficacy. However, this also complicates the characterization of allergoids using techniques as for native allergen extracts," scientists in Madrid, Spain report.

"The objective of this study was to analyse the molecular size of Betula alba depigmented allergoids, conservation of major allergens in the allergoids and in vivo antibody response to immunization. The molecular size of depigmented allergoids was evaluated by high performance-size exclusion chromatography and light scattering techniques. Protein composition was compared with native extracts by...


Source: Vaccine Weekly (2009-03-18)

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