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Vaccine Weekly

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Cancer Vaccines



New cancer vaccines study findings have been published by X.X. Song and colleagues



March 18th, 2009

"Despite advances in the development of human papillomavirus (HPV) prophylactic vaccines, little progress has been made in the field of therapeutic vaccines in recent years. In the present study, we found a significant accumulation of immature myeloid cells (ImC) in large TC-1 tumors and demonstrated that a HPV therapeutic vaccine restored antitumor immune responses with the correction of aberrant myeloid cell differentiation by all-trans retinoic acid (ATRA)," researchers in Beijing, People's Republic of China report.

"Our study demonstrated that combining ATRA with vaccination not only decreased the number of Gr-1(+) CD11b(+) ImC, but for the first time also...


Source: Vaccine Weekly (2009-03-18)

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