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DNA Research
Investigators at National Institutes of Health publish new data on DNA research
March 18th, 2009
According to recent research from the United States, "Vaccinia virus encodes a 90-kDa protein conserved in all poxviruses, with DNA primase and nucleoside triphosphatase activities. DNA primase products, synthesized with a single stranded phi X174 DNA template, were resolved as dinucleotides and long RNAs on denaturing polyacrylamide and agarose gels." "Following phosphatase treatment, the dinucleotides GpC and ApC in a 4:1 ratio were identified by nearest neighbor analysis in which P-32 Was transferred from [alpha-P-32]CTP to initiating purine nucleotides. Differences in the nucleotide binding sites for initiation and elongation were suggested by the absence of CpC and...
Source: Vaccine Weekly (2009-03-18)
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