Ebola Hemorrhagic Fever
Research findings from Emory University update understanding of ebola hemorrhagic fever
Published in Vaccine Weekly, March 18th, 2009
"Ebola virus-like particles (VLPs) were produced in insect cells using a recombinant baculovirus expression system and their efficacy for protection against Ebola virus infection was investigated. Two immunizations with 50 mu g Ebola VLPs (high dose) induced a high level of antibodies against Ebola GP that exhibited strong neutralizing activity against GP-mediated virus infection and conferred complete protection of vaccinated mice against lethal challenge by a high dose of mouse-adapted Ebola virus," investigators in the United States report.
"In contrast, two immunizations with 10 mu g Ebola VLPs (low dose) induced 5-fold lower levels of antibodies against GP and...
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Source: Vaccine Weekly (2009-03-18)
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