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Cancer Vaccines
Data on cancer vaccines published by researchers at University of Virginia, Department of Surgery
March 18th, 2009
Data detailed in 'Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules' have been presented. In this recent report published in the journal Cancer Immunology, Immunotherapy, researchers in the United States conducted a study "To test the hypothesis that decrease in DNA methylation will increase the expression of cancer-testis antigens (CTA) and class I major histocompatibility complex (MHC)-encoded molecules by ovarian cancer cells, and thus increase the ability of these cells to be recognized by antigen-reactive CD8(+) T cells. Human ovarian cancer cell...
Source: Vaccine Weekly (2009-03-18)
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