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Melanoma Vaccines



College of Medicine details research in melanoma vaccines



March 18th, 2009

A report, 'Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma,' is newly published data in Cancer Immunology, Immunotherapy. "Anti-tumor vaccines capable of activating both CD4 and CD8 T cells are preferred for long lasting T cell responses. Induction of a tumor-specific T-cell response can be induced by tumor vaccines that target innate immunity," researchers in the United States report.

"The ensuing T-cell response depends on efficient antigen presentation from phagocytosed cargo in the antigen presenting cell and is augmented by the presence of Toll-like...


Source: Vaccine Weekly (2009-03-18)

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