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Vaccine Weekly

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Emory University



Novel pandemic flu vaccine effective against H5N1 in mice



March 18th, 2009

Vaccines against H5N1 influenza will be critical in countering a possible future pandemic. Yet public health experts agree that the current method of growing seasonal influenza vaccines in chicken eggs is slow and inefficient.

Scientists at the Emory Vaccine Center have developed an alternative: virus-like particles, empty shells that look like viruses but don't replicate. Mice immunized by nose drops with the virus-like particles (VLPs) were protected for months against an otherwise lethal H5N1 infection.

The results are described in the March issue of PLoS ONE (Public Library of Science ONE).

"These results suggest that VLPs...


Source: Vaccine Weekly (2009-03-18)

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