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Vaccine Weekly

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Emory University



Vitamin a signals offer clues to treating autoimmunity



March 18th, 2009

Distributed around the body, dendritic cells act as the security alarms of the immune system. After sensing the presence of intruders, dendritic cells can transmit the alarm to white blood cells or tell them to relax, depending on the signals they send out.

Researchers at the Emory Vaccine Center and Yerkes National Primate Research Center have discovered that dendritic cells can respond to the same compound, through two different receptors, by sending out both stimulatory and calming messages at once.

The compound is zymosan, a component of yeast cell walls. However, the finding could guide scientists in designing vaccines against many infectious...


Source: Vaccine Weekly (2009-03-18)

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