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Life Sciences
Scientists at University of California describe research in life sciences
March 25th, 2009
"Polymeric carriers designed to encapsulate protein antigens have great potential for improving the efficacy of vaccines and immunotherapeutics for diseases such as cancer. We recently developed a carrier system based on polyacrylamide hydrogel microparticles cross-linked with acid-labile moieties," scientists writing in the journal Bioconjugate Chemistry report. "After being phagocytosed by antigen-presenting cells, the protein encapsulated within the carrier is released and processed for subsequent presentation of antigenic epitopes. To understand the impact of particle size on the activation of T-cells following uptake by antigen-presenting cells, particles...
Source: Vaccine Weekly (2009-03-25)
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