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Melanoma
Researchers from University of Pittsburgh describe findings in melanoma
March 25th, 2009
According to a study from the United States, "High-dose interferon (IFN)alpha-2b has shown benefits in the adjuvant treatment of melanoma, but relapse-free and overall survival remain poor, despite the use of chemotherapy, vaccines, and combinations of these modalities. Questions remain in relation to the relative importance of dose, route and duration of immunotherapy needed to prevent relapse and improve survival." "Our understanding of STAT signaling, the role of dendritic and T cells and of circulating cytokine profiles in this benefit of IFN therapy have yet to be deployed clinically. The EORTC 18991 trial analyzed whether pegylated IFN alpha-2b delivered for up to...
Source: Vaccine Weekly (2009-03-25)
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