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Gene Therapy
Studies in the area of gene therapy reported from University of Strasbourg
March 25th, 2009
In this recently published article, scientists in Illkirch-Graffenstaden, France conducted a study "To design and evaluate liposomal constructs capable of inducing a potent systemic and airway humoral response to Pseudomonas aeruginosa Methods. Liposomes contained a peptide derived from P. aeruginosa pilin protein as B epitope, a peptide derived from Influenza hemagglutinin protein as Th epitope, the TLR agonist Pam(3)CAG or Pam(2)CAG as adjuvant, and a mannosylated lipid as dendritic cell targeting agent." "These constructions were administered to mice intraperitoneally (i.p.) or intranasally (i.n.). Their immunogenicity was evaluated by measuring B epitope-specific...
Source: Vaccine Weekly (2009-03-25)
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