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Vaccine Weekly

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Immunization



New immunization research reported from Zhejiang University, Medical Department



March 25th, 2009

"The hygiene hypothesis suggests a lack of bacterial infections would favor the development of allergic diseases. Mycobacterium bovis bacille Calmette-Guerin (BCG) infection can inhibit allergen-induced asthma reactions, but the underlying mechanism of this infection on the immunological responses is unclear," scientists writing in the journal Acta Pharmacologica Sinica report.

"T-regulatory (Treg) cells are thought to play a role as a crucial immunoregulatory cells that are capable of regulating adaptive immune responses. We conducted this study to investigate whether the protective effect of the BCG vaccination on allergic pulmonary inflammation is associated...


Source: Vaccine Weekly (2009-03-25)

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