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Influenza
Research from University of Rochester provide new insights into influenza
April 1st, 2009
"The rise in influenza-specific neutralizing antibody levels is proceeded by a burst of antigen-specific antibody secreting cells (ASC) or plasmablasts identified in peripheral blood approximately 5-10 days post immunization. Blood antigen-specific ASC may function as an immune marker of vaccine responses in comparison to the pre- and post-neutralizing titers; however, some have questioned whether there is adequate survival of ASC isolated from peripheral blood after freezing, making multi-center vaccine trials difficult," investigators in the United States report. "Here, we demonstrate similar frequencies of influenza-specific ASC from fresh and frozen peripheral blood...
Source: Vaccine Weekly (2009-04-01)
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