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Vaccine Weekly

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Atopic Dermatitis



Data on atopic dermatitis reported by researchers at Mie University, Medical Department



April 1st, 2009

According to a study from Tsu, Japan, "Increase in the number of patients with atopic dermatitis (AD) has been recently reported. T helper (Th) cells that infiltrate AD skin lesions are Th2-type dominant; reduced exposure to environmental Th1-cytokine-inducing microbes is believed to contribute to the increased number of AD patients."

"Regulatory type immune responses have been also associated with the occurrence of AD. It has been reported that antigen 85B (Ag85B) purified from mycobacteria is a potent inducer of Th1-type immune response in mice as well as in humans. In this study, we have examined the effect of plasmid DNA encoding Ag85B derived from Mycobacterium...


Source: Vaccine Weekly (2009-04-01)

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