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Immunization
Studies from Indian Institute of Chemical Biology further understanding of immunization
April 1st, 2009
Research findings, 'Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection,' are discussed in a new report. "BALB/c mice immunized intraperitoneally (i.p.) and intravenously (i.v.) with Leishmania donovani promastigote membrane antigens (LAg), either free or encapsulated in liposomes, were protected against challenge infection with L. donovani, whereas mice immunized by the subcutaneous (s.c.) and intramuscular routes were not protected. Protected mice showed strong parasite resistance in both the liver and spleen, along with enhanced immunoglobulin G2a and delayed-type...
Source: Vaccine Weekly (2009-04-01)
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