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Plague Gene Therapy
New research on plague gene therapy from Weill Cornell Medical College, Department of Genetic Medicine summarized
April 1st, 2009
New investigation results, 'Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge,' are detailed in a study published in Infection and Immunity. According to recent research from the United States, "Pneumonic plague, caused by inhalation of Yersinia pestis, represents a major bioterrorism threat for which no vaccine is available. Based on the knowledge that genetic delivery of monoclonal antibodies (MAbs) with adenovirus (Ad) gene transfer vectors results in rapid, high-level antibody expression, we evaluated the hypothesis that Ad-mediated delivery of a neutralizing antibody directed against the Y. pestis V...
Source: Vaccine Weekly (2009-04-01)
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