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Tuberculosis Vaccines



Investigators at Kuwait University, Department of Microbiology release new data on tuberculosis vaccines



April 1st, 2009

Data detailed in 'Th1 cell reactivity and HLA-DR binding prediction for promiscuous recognition of MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis' have been presented. According to a study from Kuwait, "MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis, is immunoreactive in antibody assays in humans and animals and provides protection as a combined DNA vaccine in mice. This study was undertaken to determine the reactivity of MPT63 in T helper 1 (Th1) cell assays, i.e. antigen-induced proliferation and interferon-gamma secretion, using peripheral blood mononuclear cells (PBMCs) obtained from 72 Mycobacterium bovis Bacille...


Source: Vaccine Weekly (2009-04-01)

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