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Vaccine Weekly

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Vaccines



Findings from Landspitali University, Department of Immunology broaden understanding of vaccines



April 1st, 2009

Current study results from the report, 'IC31, a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice,' have been published. "IC31 is a novel adjuvant which combines the immunostimulatory effects of an 11-mer antibacterial peptide (KLKL(5)KLK) and a synthetic oligodeoxynucleotide (ODN1a) which is a Toll-like receptor 9 agonist without containing cytosine phosphate guanine (CpG) motifs. The effects of IC31 on neonatal immune response to vaccination have not been reported," researchers in Reykjavik, Iceland report.

"Neonatal mice were immunized once or twice with a Streptococcus...


Source: Vaccine Weekly (2009-04-01)

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