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Vaccines
Study findings from Fudan University, Engineering Institute broaden understanding of vaccines
April 1st, 2009
Scientists discuss in 'More vaccine efficacy studies on the recombinant Bacille Calmette-Guerin co-expressing Ag85B, Mpt64 and Mtb8.4' new findings in vaccines. "The immunogenicity of the recombinant Bacille Calmette-Guerin: rBCG-Ag85B-Mpt64(190-198)-Mtb8.4 (rBCG-AMM) was evaluated in our previous study. This paper compares the protective efficacy of rBCG-AMM, rBCG-A which overexpresses Ag85B and BCG in C57BL/6 mice," investigators in Shanghai, People's Republic of China report. "There was no significant difference in proliferation characteristics among rBCG-AMM, rBCG-A and BCG. The growth characteristics of rBCG-AMM in host tissue were identical to control BCG,...
Source: Vaccine Weekly (2009-04-01)
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