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Vaccine Weekly

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HIV/AIDS



Reports from Charite University advance knowledge in HIV/AIDS



April 1st, 2009

In this recent article published in the journal AIDS, scientists in Berlin, Germany conducted a study "Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. TLR7 recognizes RNA of various viruses including HIV."

"The objective of this study was to examine the influence of individual genetic variations of TLR7 on the susceptibility to and progression of HIV disease. We genotyped a population of 734 HIV-positive adults and 545 healthy controls for three TLR7 single nucleotide polymorphisms. The frequency of TLR7 genetic variations was assessed and related to HIV disease progression. Furthermore, we analyzed peripheral blood...


Source: Vaccine Weekly (2009-04-01)

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