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DNA Vaccines
New DNA vaccines research from Huazhong Agricultural University outlined
April 1st, 2009
According to a study from Wuhan, People's Republic of China, "We constructed a suicidal DNA vaccine pSFV-ORF5m/ORF6 co-expressing GP5m (a modified GP5) and M proteins of porcine reproductive and respiratory syndrome virus (PRRSV)." "In mice immunization, specific immune responses were elicited by the suicidal DNA vaccine pSFV-ORF5m/ORF6. The immunogenicity and protective efficiency was then evaluated in piglets immunized with pSFV-ORF5m/ORF6 before virus challenge: PRRSV-specific neutralizing antibodies and lymphocyte proliferative responses were developed," wrote Y.B. Jiang and colleagues, Huazhong Agricultural University. The researchers concluded:...
Source: Vaccine Weekly (2009-04-01)
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