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Immunization
Data on immunization reported by researchers at Jawaharlal Nehru University
April 1st, 2009
According to recent research published in the European Journal of Immunology, "Based on the hypothesis that immune outcome can be influenced by the form of antigen administered and its ability to access various antigen-processing pathways, we targeted the 63 kDa fragment of protective antigen (PA) of Bacillus anthracis to various subcellular locations by DNA chimeras bearing a set of signal sequences. These targeting signals, namely, lysosome-associated membrane protein 1 (LAMP1), tissue plasminogen activator (TPA) and ubiquitin, encoded various forms of PA viz. lysosomal, secreted and cytosolic, respectively." "Examination of IgG subclass distribution arising as...
Source: Vaccine Weekly (2009-04-01)
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