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Vaccine Weekly

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Encephalitis



Scientists at Huazhong Agricultural University report research in encephalitis



April 8th, 2009

According to recent research from Wuhan, People's Republic of China, "Transgenic plants have become attractive as bioreactors to produce heterologous proteins that can be developed as edible vaccines. In the present study, transgenic rice expressing the envelope protein (E) of Japanese encephalitis virus (JEV), under the control of a dual cauliflower mosaic virus (CaMV 35S) promoter, was generated by Agrobacterium-mediated transformation."

"Southern blot, Northern blot, Western blot and ELISA analyses confirmed that the E gene was integrated into transgenic rice and was expressed in the leaves at levels of 1.1-1.9 mu g/mg of total soluble protein. After intraperitoneal...


Source: Vaccine Weekly (2009-04-08)

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