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HIV/AIDS
Research on HIV/AIDS described by scientists at Johns Hopkins University
April 8th, 2009
According to recent research published in the journal AIDS Research and Human Retroviruses, "Vaccines inducing pathogen-specific cell-mediated immunity are being developed using attenuated adenoviral (Ad) vectors. We report the results of two independent Phase I trials of similar replication-deficient Ad5 vaccines containing a near-consensus HIV-1 clade B gag transgene." "Healthy HIV-uninfected adults were enrolled in two separate, multicenter, dose-escalating, blinded, placebo-controlled studies to assess the safety and immunogenicity of a three-dose homologous regimen of Ad5 and MRKAd5 HIV-1 gag vaccines given on day 1, week 4, and week 26. Adverse events were...
Source: Vaccine Weekly (2009-04-08)
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